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Wednesday, December 24, 2014

Your blood type can predict your increased or decreased risk of heart attack, stroke and dementia

Your blood type can predict your increased or decreased risk of heart attack, stroke and dementia

The good news is that your can modify the risks.

Blood type and thinking ability
A study published in Neurology Sep. 2014 involving 587 participants found that impairment in thinking was around 82 percent more likely in those with type AB blood than those with type A, B or O even after taking their race, sex and geography into account.

Blood type and cardiovascular disease
A person's blood type may affect their risk for heart disease, but healthy lifestyle can still make a difference to protect people with the higher risk blood types.

A 20 year follow up of 90,000 Participant adults found those with blood type AB had a 23% increased risk for heart disease, those with type B had an 11% increased risk, and those with type A had a 5% increased risk, compared to people with type O.

Possible  causes
1. Blood type A is linked to higher levels of low-density lipoprotein (LDL) cholesterol, the "bad" cholesterol that clogs up arteries

2. Blood type AB is linked to inflammation, which can affect how blood vessels work.

3. People with blood type O have higher levels of a compound that has a beneficial effect on blood flow and clotting.

Supplements that may help
Given that inflammation may be major contributing factor and dietary intakes of fish oils and turmeric (Curcumin) may help reduce this inflammation.

This could be one of the reasons these supplements have been found to have a positive health benefit on cardiovascular disease, mental health and memory function.

Curcumin and Alzheimer ’s disease.  several studies have found that curcumin reduces oxidative damage and inflammation  and reduces amyloid accumulation and synaptic marker loss while promoting both amyloid phagocytosis and clearance. 

These actions are consistent with a reduced progression to memory loss and Alzheimer's disease

Russell's suggestions

Blackmores Brain Active (optimised curcumin)
one capsule daily

Fish Oil 1000mg 
three capsules daily

1. Neurology September 2014

2. Arteriosclerosis, Thrombosis and Vascular Biology August 2012

3. Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice. Ma QL, Zuo X, Yang F, Ubeda OJ, Gant DJ, Alaverdyan M, Teng E, Hu S, Chen PP, Maiti P, Teter B, Cole GM, Frautschy SA. J Biol Chem. 2013 Feb 8;288(6):4056-65.

4. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study. Ringman JM, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, Gylys KH, Badmaev V, Heath DD, Apostolova LG, Porter V, Vanek Z, Marshall GA, Hellemann G, Sugar C, Masterman DL, Montine TJ, Cummings JL, Cole GM. Alzheimers Res Ther. 2012 Oct 29;4(5):43.

5. Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease. Hickey MA, Zhu C, Medvedeva V, Lerner RP, Patassini S, Franich NR, Maiti P, Frautschy SA, Zeitlin S, Levine MS, Chesselet MF. Mol Neurodegener. 2012 Apr 4;7:12. doi: 10.1186/1750-1326-7-12.

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